Without any doubt, Alzheimer’s disease is recognized as a serious disease worldwide.
Ranked on sixth as the most death and fatal disease in the USA, the studies about Alzheimer’s have found that this disease comes after cancer and heart diseases.
One needs to be very careful and vigilant if he gets noticed of such symptoms.
What is Alzheimer’s disease?
This disease defined as the most common cause of dementia in old-aged people. Dementia is defined as the condition where a victim loses his cognitive functioning, such as memorizing, reasoning, and thinking.
It implies that the person’s behavioral abilities intersect, which affects his personal life inefficiently.
A person suffering from Alzheimer’s is recognized from its causes.
The causes of this disease vary and depend on brain changes types that keep on taking place. The name of the disease is named after Dr. Aloes Alzheimer’s.
He was the first person who recognized the brain tissue of a dead woman in the year 1906.
For this disease, the symptoms are speaking problems, unexpected behavior, and memory loss.
After the death of a woman, the doctor thoroughly examined her brain and observed various normal clumps and numerous bundles of fibers.
Plaques and tangles in the brain are identified as the primary features of Alzheimer’s disease.
One of the other primary features includes loss of connections between nerve cells or neurons in the brain.
These neurons transmit messages from different muscles and organs of the body to the brain.
Changes in the Brain
The multifarious part of the human component is the brain. The experiments behind understanding the complexities of the brain by many scientists are endless, which include the study for Alzheimer’s disease as well.
It appears as if the damage to the diseased brain initiates about a decade or more before the stage of memory loss and other problems.
However, the brain has many toxic changes involved. Fibers and plaques are formed by the abnormal deposits of the proteins in the brain.
This prevents functioning and leads to losing connectivity with the neurons. After losing the connection, these neurons die.
The very early instances of development of this damage are observed in the hippocampus. It means that damage initiates from the hippocampus.
This leads to memories affected because this part is associated with forming memories.
When the number of neurons dies the additional parts of the brain get adversely affected, which leads to the shrinkage of those parts.
The damage appears to occur in the hippocampus at the beginning. This is the part of the brain vital in developing memories.
As more neurons die, additional parts of the brain are affected, and they begin to shrink.
By the time the final stage of Alzheimer’s disease appears, the damage is already widespread, and the substantial part of the brain has already shrunk.
What Causes Alzheimer’s?
The actual cause of the disease has not been detected by the scientists yet but the search is on and we will get the detailed answers shortly perhaps.
But there are some estimates which have been put forth by scientists.
There is some genetic component involved in the early stage of the disease whereas the late-onset disease rises from very tangled brain changes that have occurred over the decades.
The cause includes a special sort of combination of genetic, environmental and lifestyle factors which one chose in his/her life.
Also, it has been noted that this disease can differ from person to person.
Those people who have the late-onset disease, come to know about it in their mid-60s.
One form is APOE ε4. It escalates a person’s risk of getting this disease. Well, there is no quick rule an individual having this gene will defiantly get affected by this disease.
There are many cases where people who suffer from this disease got affected even they were not surfing from such genes.
Health, Environmental, and Lifestyle Factors
According to many researchers, there are certain factors that affect the health of a person due to genetics in excess.
Those suffering from diabetes are generally at a high risk of suffering from both dementia and Alzheimer’s.
So, in order to live a life without Alzheimer’s, one needs to maintain a healthy and active lifestyle, which is backed by proper mental & physical exercise and a nutritious diet.
Signs and Symptoms
There is a substantial amount of problem or damage that Alzheimer’s starts to show some signs.
The primary feature of this disease is a memory problem. Cognitive impairment is the first sign.
In this MCI, people get more memory problems which are mentioned as average according to their particular age.
Well, it doesn’t have any effect on one’s daily schedule.
It has to be taken care that the symptoms vary from person to person. For a lot of people, it might be a decline in the memory and for some; it can be non-memory aspects of cognition which include loss of word, vision issues, and impaired judgment.
Many researchers are studying biomarkers and their uses to find out if they can be of any importance in the detection of the early changes in the brain.